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B-QuiCK: UTI

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B-QuiCK: UTI

The diagnosis and management of symptomatic lower UTIs in adults

Table 1. Empiric antibiotic regimens for uncomplicated UTI in adults. N.B. Treat for seven days in pregnant females and in all males, regardless of antibiotic choice.

Antibiotic

Dose

First line

Nitrofurantoin*†

Modified-release (Macrobid): 100 mg, twice daily, for five days

Immediate-release (Nifuran): 50 mg, four times daily, for five days

Alternatives
(see note below)

Cefalexin

500 mg, twice daily, for three days

Trimethoprim‡

300 mg, once daily at night, for three days

N.B. Regional guidelines differ in alternative antibiotic recommendations. This may be due to local resistance and sensitivity patterns. If an alternative antibiotic is needed, check for local advice, e.g. HealthPathways, and follow corresponding recommendations if available.

* Prescribe by brand name to reduce errors as there are two different formulations

† Avoid after 36 weeks gestation in pregnant patients and in those with creatinine clearance < 60 mL/min due to the risk of peripheral neuropathy

‡ Avoid during the first trimester of pregnancy

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It is strongly recommended to review the original resource at your convenience for full details of recommendations and evidence.

See full article here: Urinary tract infections (UTIs) – an overview of lower UTI management in adults

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