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B-QuiCK: UTI

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B-QuiCK: UTI

The diagnosis and management of symptomatic lower UTIs in adults

Table 1. Empiric antibiotic regimens for uncomplicated UTI in adults.

N.B. Treat for seven days in pregnant females and in all males, regardless of antibiotic choice.

	Antibiotic	Dose
First-line	Nitrofurantoin^*†	Modified release (Macrobid): 100 mg, twice daily, for five days Immediate release (Nifuran): 50 mg, four times daily, for five days
Alternatives	Cefalexin	500 mg, twice daily, for three days
Trimethoprim^‡	300 mg, once daily, for three days

Antibiotic

Dose

First-line

Nitrofurantoin^*†

Modified release (Macrobid): 100 mg, twice daily, for five days

Immediate release (Nifuran): 50 mg, four times daily, for five days

Alternatives

Cefalexin

500 mg, twice daily, for three days

Trimethoprim^‡

300 mg, once daily, for three days

^* Contraindicated in patients with a creatine clearance < 60 mL/min due to the risk of peripheral neuropathy. Prescribe nitrofurantoin by brand name to reduce errors as there are two different formulations. Nitrofurantoin is not an appropriate first-line choice in patients with suspected pyelonephritis as it is associated with poor tissue penetration.

^† Avoid after 36 weeks gestation in pregnant females

^‡ Avoid in the first trimester of pregnancy

It is strongly recommended to review the original resource at your convenience for full details of recommendations and evidence.

See full article here: Urinary tract infections (UTIs) – an overview of lower UTI management in adults

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B-QuiCK: UTI

B-QuiCK: UTI

The diagnosis and management of symptomatic lower UTIs in adults

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