Fusidic acid 2% cream or ointment
Apply twice daily, for five days
N.B. Use topical Fusidic acid as second line treatment after topical antiseptics and only if the infection is localized.
If topical treatment fails, use oral treatment as above.
Trimethoprim + sulphamethoxazole* (if complicated infection, MRSA present† or allergy to flucloxacillin)
Child > 6 weeks:24 mg/kg/dose, twice daily, for five days (maximum 20 mL/dose)
Child > 12 years and Adult: 960 mg (two tablets), twice daily, for five days
* Formerly referred to as co-trimoxazole oral liquid 40+200 mg/5ml or co-trimoxazole tablets 80+400 mg;
now expressed as the total dose of trimethoprim + sulfamethoxazole (ratio 1:5) - 240 mg/5 mL oral liquid or 480 mg tablets.
N.B. avoid in infants aged under six weeks, due to the risk of hyperbilirubinaemia.
(if allergy to flucloxacillin or MRSA present†)
Child aged < 12 years: 20 mg/kg/dose, twice daily, or 10 mg/kg/ dose, four times daily, for five days (maximum 1.6 g/day)
Adult: 800 mg, twice daily, or 400 mg, four times daily, for five days
† Based on MRSA susceptibilities
(if flucloxacillin not tolerated)
Child: 12–25 mg/kg/dose, twice daily, for five days
Adult: 500 mg, four times daily or 1 g, twice daily, for five days