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Safer prescribing of high-risk medicines

Note: Article series are online compilations of previously published articles, links will open in a new window to the original article.

Safer prescribing of high-risk medicines: Clozapine

Pharmacological treatment is an integral part of the practice of medicine, and is one of the most significant factors in improving patient health. However, some medicines, when used outside of therapeutic indications or doses, or even when used appropriately, can become a “poison” rather than a “cure”.

Best Practice Journal, July 2014

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Safer prescribing of high-risk medicines: Colchicine – extremely toxic in overdose

Colchicine is a plant-based alkaloid, extracted from Colchicum autumnale (autumn crocus, meadow saffron) and Gloriosa superba (glory lily) used to treat gout and some other inflammatory conditions. It is considered a high-risk medicine because it is associated with significant toxicity when not used correctly.

Best Practice Journal, September 2014

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Safer prescribing of high-risk medicines - Methotrexate: potentially fatal in overdose

Low-dose methotrexate is commonly used in the treatment of patients with rheumatoid arthritis and other rheumatologic diseases, as well as severe psoriasis. It is an effective medicine for these indications, however, it can also be highly toxic.

Best Practice Journal, October 2014

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