General practice plays an important role in managing urinary incontinence
Urinary incontinence is defined as self-reported involuntary leakage of urine.1 Incontinence is usually
associated with ageing, childbirth or menopause. However, incontinence can occur secondary to conditions such as heart
failure, stroke, multiple sclerosis and diabetes; as a result of trauma or after surgery; and as an adverse effect of
some medicines, such as loop diuretics.
Approximately 10% of people experience urinary incontinence at some point in adulthood, and incidence increases with
age.1 Incontinence is approximately six times more common in females than in males.1 This means
that incontinence is often viewed as a condition exclusive to females. However, incontinence is prevalent in certain groups
of males, such as those who have undergone any prostate surgery.
The impact of urinary incontinence on a patient’s quality of life can be significant. Most complications of incontinence
are psychosocial, including depression, feelings of shame, loss of self-confidence, lower perceived sense of wellbeing,
social isolation, sexual dysfunction and financial difficulties (due to the cost of pads, bedding, laundry and reduced
ability to work).2 Loss of sleep, and falls and fractures (due to hurrying to the bathroom) are also often
Treatment initially focuses on lifestyle changes and behavioural interventions, such as pelvic floor muscle exercises
and bladder training. If these are ineffective, pharmacological treatments can be trialled, depending on the type of incontinence.
Surgical options are available for some types of urinary incontinence, particularly stress incontinence, if conservative
treatments are unsuccessful.
The prognosis for people with urinary incontinence depends on the type of incontinence, the severity, the underlying
cause(s), any contributing factors and the individual’s motivation for treatment. However, most incontinence can be substantially
improved even where it cannot be “cured”.
Urinary incontinence in females
Urinary incontinence in females is usually divided into: stress incontinence, urgency incontinence, mixed incontinence,
overactive bladder and overflow incontinence. Stress and urgency incontinence account for 90% of all cases of incontinence
The most significant risk-factors for incontinence are older age and previous pregnancy with a vaginal delivery.2 Obesity
and having a family history of incontinence also increase the likelihood of developing incontinence.2
Types of urinary incontinence
Stress incontinence is defined as leakage associated with physical activity or increased intra-abdominal pressure, such
as coughing, sneezing or rising from a chair.5 It occurs in 25 – 45% of females aged over 30 years.5 It
is caused by atrophy or damage to the pelvic floor muscles, ligaments or fascia. This is usually associated with childbirth
and menopause (See: “Pelvic organ prolapse”).
Urgency incontinence is leakage associated with, or immediately after, the sudden need to void (termed urgency). The
volume of urine lost is variable, and total emptying of the bladder, known as complete incontinence, may occur. Urgency
incontinence occurs due to detrusor muscle overactivity. This overactivity may be neurogenic, secondary to an underlying
pathology or idiopathic. Neurogenic overactivity of the bladder can result from any condition that causes loss of neurological
control, most commonly stroke, multiple sclerosis, spinal cord injury or spina bifida.5 Secondary causes of
incontinence include urinary tract infection (UTI), sexually transmitted infections (STI), interstitial cystitis, atrophic
vaginitis, bladder diverticula or prior pelvic radiation or surgical treatment. Idiopathic overactivity is poorly understood,
but occurs with ageing, and is closely linked with overactive bladder syndrome.
Overactive bladder syndrome is a largely idiopathic urological condition comprising urgency, frequency
and, often, nocturia.6 Urgency incontinence with no known cause is often referred to as overactive bladder.
However, in people with overactive bladder, urgency and frequency can occur without any resulting incontinence. The frequency
of voiding will generally be more than eight times per day.2 The cause of overactive bladder is not well understood,
but loss of neurological control of the detrusor muscle activity is thought to contribute to the condition.6 Overactive
bladder is managed in the same way as urgency incontinence.2
Mixed incontinence is defined as a combination of stress and urgency incontinence, and occurs in approximately one-third
of females with incontinence.1 Mixed incontinence becomes more common with age as multiple disease states
begin to occur, e.g. idiopathic urgency incontinence begins to develop in a woman with a weak pelvic floor that is causing
stress incontinence. Management should follow the individual management of each type of incontinence, but with a focus
on the dominant type.2
Overflow incontinence occurs when there is obstruction at the bladder neck or an impairment of detrusor
contractility, so that leakage occurs from an over-filled bladder, often without urgency. It is more commonly seen in
males. Overflow incontinence can be caused by urethral obstruction, prolapse of the pelvic organs, neurological damage
and conditions that can reduce sensation in the bladder, such as stroke, multiple sclerosis and diabetes.
Other forms/causes of incontinence include:
- Functional incontinence occurs when cognitive or physical impairments prevent the patient from voiding
independently and appropriately
- Post-void dribbling is leakage occurring after voiding due to urine remaining in the urethra
- Urogenital fistula, where a passage opens between the bladder/urethra and the vagina, bypassing the
urethral sphincter. Urogenital fistula can cause complete incontinence. Among women in the developed world, this occurs
most often due to complications from gynaecological surgery, e.g. hysterectomy.
How does the bladder work?
The bladder is a muscular reservoir for urine that sits behind the pubic symphysis. A normal bladder in an adult holds
between 300 – 600 mL of urine.3 When healthy, bladder function is controlled by coordination between musculoskeletal
and neurological inputs.3
Neurological control of the bladder is bi-phasic, operating like a switch: alternating between storage or voiding.4 The
neural pathways controlling voiding are complex and involve the brain, spinal column and peripheral ganglia. These pathways
involve autonomic (sympathetic and parasympathetic) and somatic nerves (via the pudendal nerve). N.B. Acetylcholine is
one of the neurotransmitters of the parasympathetic pathways which mediate detrusor contraction, so this is why anticholinergic
medicines are used to stabilise the bladder.
Damage to any of these structures or neural pathways can lead to incontinence.4 Afferent and efferent nerve
fibres involving bladder control are mainly located at the S2–S4 spinal nerve levels (but also involve the T11–L2 spinal
segments),4 so spinal cord injuries at the sacral level often affect continence. The frontal lobes of the
brain provide inhibitory input, suppressing inappropriate bladder voiding,4 therefore incontinence can result
from damage to the frontal lobes, such as in people who have had a stroke or with dementia. Surgical procedures involving
the urogenital system, such as prostatectomy in males, may damage the adjacent external urethral sphincter or the urethra
itself, leading to incontinence.
In healthy person, voiding is under conscious control, and relies on learned behaviours that develop during childhood.4 Mechanical
control of continence involves the muscles and connective tissue surrounding the bladder.3 The bladder neck
and pelvic floor musculature work together to increase outflow resistance to a point where it is greater than the outflow
pressure created by the resting bladder.3 Acute spikes of pressure also occur with daily activities, such
as coughing, standing up and laughing. If the pelvic floor muscles have sufficient tone, the guarding reflex increases
urethral pressure as outflow pressure increases, maintaining continence. If the outflow resistance is less than these
spikes of pressure, such as when pelvic floor support is lost, leakage occurs. Outflow pressure also increases when the
detrusor muscles contract. This occurs consciously during normal voiding, but may also occur unconsciously with overactivity
in the bladder, causing incontinence.
Medicines that may cause, contribute to or worsen incontinence9, 10
||How it causes incontinence
Sympathomimetics, e.g. pseudoephedrine
Tightening of the urinary sphincter can cause urine to be retained, leading to overflow incontinence
Alpha blockers, e.g. doxazosin
Relaxes the urinary sphincter and urethra; potentially causing stress incontinence
ACE inhibitors, e.g. cilazapril
Can cause cough and worsen stress incontinence
Tricyclic antidepressants, e.g. amitriptyline
Anticholinergic effect can interfere with bladder contraction and cause constipation leading to urinary retention
and overflow incontinence
Antihistamines, e.g. promethazine
Anticholinergic effect as above
Antipsychotics, e.g. haloperidol, risperidone, quetiapine
Anticholinergic effect as above, and can also reduce physical mobility and cause abrupt urgency incontinence
Calcium channel blockers, e.g. diltiazem
Interfere with bladder contraction and worsen constipation leading to urinary retention and overflow incontinence
Diuretics, e.g. furosemide
Increase urine production, potentially worsening all types of incontinence
Vitamin and mineral supplements, particularly iron
Can cause constipation and urinary retention leading to overflow incontinence11
Opioids, e.g. oxycodone
Can interfere with bladder contraction and worsen constipation leading to urinary retention and overflow incontinence
Sedatives, e.g. diazepam
Can slow mobility and cause urgency incontinence
History and examination
As urinary incontinence is initially diagnosed based on the patient’s report of symptoms, the focus of the history and
examination should be on assessing the patient to determine the type, underlying factors, severity and impact of their
See Red flags in patients with urinary incontinence
Enquire about the following factors when taking a patient history:7
- Frequency of voiding
- Frequency of leakage (how many times per day, how many days in a typical week) and the volume of urine leaked
- The triggers associated with leakage, i.e. does leakage occur when the patient laughs? When they are lying flat in
- The use of pads or other protective devices
- Diet and fluid intake, including caffeine and alcohol intake
- Lower urinary tract symptoms, e.g. UTI symptoms, post-void dribbling, needing to urinate again immediately after voiding1
- Other genitourinary symptoms, e.g. urogenital or abdominal pain, discomfort, haematuria, other discharge
- Constipation and faecal incontinence/soiling*
- Sexual function (i.e. psychosocial effects of incontinence)
- Past history of: bladder surgery, hysterectomy, childbirth (including number of births and mode of deliveries), previous
UTI, previous STI
- Medicine use (see: “Medicines that may cause incontinence”)
- Smoking status**
* The rectum and bladder share similar neural pathways, and dysfunction of one often leads to dysfunction in the other,
either neurologically or mechanically.
** Cigarette smoking is associated with bladder overactivity, is thought to be a bladder irritant and causes chronic
cough, which may weaken the pelvic floor over time, and will directly influence the severity of stress incontinence.8
Determining the type of incontinence
At this point in the assessment the type of incontinence is likely to be apparent.
The following incontinence types are more likely depending on when the leakage of urine occurred:2
- Stress urinary incontinence – when coughing, sneezing, laughing, lifting or exercising
- Urgency incontinence, with or without overactive bladder syndrome – sudden urgency, often accompanied by frequency
and nocturia, particularly if the patient is in bed and lying still (i.e. there is no stress)
- Mixed incontinence – both types of symptoms are present
If incontinence is not associated with the above causes (which will be rare), consider:2
- Chronic urinary retention associated with bladder overflow incontinence or a bladder outlet obstruction – voiding
difficulty (hesitancy, straining to void, poor or intermittent urinary stream, and post-void dribbling)
- Fistula (vesicovaginal, urethrovaginal or ureterovaginal – constant passive leakage of urine and often complete incontinence
- Urethral diverticulum – post-void dribbling, frequency, dyspareunia and dysuria, particularly in a woman with recurrent
A urethral diverticulum is an out-pouching of the urethra of uncertain aetiology. It most commonly occurs in females
aged 30 – 60 years. Urine stagnates in this pouch and can predispose the patient to recurrent infections. If the diverticulum
is large, it may cause bladder outlet obstruction. Over time, chronic inflammation may lead to malignant transformation
of the cells lining the urethral diverticulum.12
The physical examination should be aimed at identifying any underlying or contributory causes to the type of incontinence
identified from the history, and include:1
- An assessment of the patient’s general health status, particularly looking for impaired mental status (i.e. confusion,
signs of dementia), obesity and reduced mobility/dexterity
- Consideration of the presence of systemic conditions that may be contributing to incontinence, e.g. uncontrolled diabetes
- Abdominal examination for masses, including an enlarged bladder (suggests potential urinary retention)
- Cough stress test (if stress incontinence is present)
- Pelvic examination – perineum and external genitalia including tissue health, signs of oestrogen deficiency, vaginal
examination with a speculum for pelvic organ prolapse, bimanual pelvic and anorectal examination for pelvic masses and
pelvic floor muscle function and tone
Cough test for stress incontinence
Stress urinary incontinence in females should ideally be confirmed with examination. To assess whether stress incontinence
is present, ask the patient to lie flat on their back and cough. Observe the external urethral meatus for leakage during
the first cough. The absence of leakage does not rule out stress urinary incontinence.
Perform a visual and digital examination of the vagina to assess for masses, structural abnormalities and for evidence
of pelvic organ prolapse, using bivalve and Sims speculums (See: “Pelvic organ prolapse”).2 During
the digital examination, feel for a soft, tender mass on the anterior vaginal wall and look for urethral discharge or
tenderness, which may indicate urethral diverticulum.
The patient’s pelvic floor musculature should ideally be assessed.2 Insert a finger into the vagina and
ask the patient to tense their pelvic floor muscles: assess both the strength and endurance of the muscle tone. This can
give a baseline from which to measure the effectiveness of treatment. It is also useful to ensure that the patient is
contracting the correct muscles, if they are going to begin pelvic floor muscle exercises while waiting for referral to
a specialist physiotherapist or nurse.
Clinicians who are experienced with assessing incontinence may grade muscle tone using a scale such as the Oxford Grading
system. Further information about this is available from:
Further examination may be carried out as indicated by the patient’s symptoms and signs. A focused neurological examination
may be appropriate to assess the likelihood of a neurological condition causing incontinence, e.g. recent stroke, multiple
Dipstick urinalysis should be performed to assess for haematuria, glycosuria and signs of infection.2
Serum creatinine is usually not necessary, but may be considered if the patient has recurrent UTI, urinary retention
or renal obstruction is suspected.
The patient should be asked to keep a bladder diary.2 The diary should cover three days
and document the amount and types of fluids consumed, how frequently they void, any episodes of urgency, any episodes
of incontinence and pad/clothing changes.2 A bladder diary has been shown to be a reliable method of quantifying
frequency, incontinence and measuring response to treatment.2
The normal volume of urine passed in each voiding is between 200 – 400 mL, and the generally accepted average voiding
frequency is four to eight times daily, including one void per night.2
An example of a bladder diary is available from:
Further testing (below) may be necessary once the bladder diary is completed, at a follow-up consultation. Some of these
tests may need to be carried out in a secondary care setting.
Post-void residual bladder volume should be assessed in patients with significant voiding symptoms, recurrent UTI, symptomatic
pelvic organ prolapse (See: “Pelvic organ prolapse”) or bladder distension.1, 7 This
should be done with a bladder ultrasound, which will require referral for those practices without a bladder scanning device
(bladder scans may not be routinely available in some regions).7 In-out catheterisation may also be used to
measure residual urine volume in bladder, but should only be considered where bladder scanning is unavailable, or if urinary
retention is noted during the examination.7
Urodynamic testing may be used in secondary care.7 Urodynamic testing measures how well the bladder and
urethra store and release urine. The test usually records flow rate, residual urine, capacity and can identify involuntary
spasm prior, during or after voiding that leads to leakage.
Pad testing, Q-tip testing, Bonney and Fluid-Bridge tests are not recommended for assessing urinary incontinence.7
Pelvic organ prolapse
Pelvic organ prolapse is a frequent cause of urinary incontinence. It usually occurs following pelvic floor damage
in childbirth, but can be multi-factorial, resulting from loss of support from the vagina, the pelvic floor musculature
and connective tissue, as well as damage to the involved neurological system.13
Traditional terms for describing pelvic organ prolapse (e.g. cystocoele, urethrocoele, rectocoele, enterocoele) have
generally been replaced. This is because the older terms imply a level of certainty about the structures causing the
vaginal bulge, particularly in females who have had previous pelvic organ prolapse surgery. Current practice is to use
terminology that divides the pelvis into anterior, posterior and middle or apical compartments.13
These terms refer to:14
- Anterior – the front wall of the vagina has herniated inward, usually caused by the bladder or/and urethra shifting
position and placing pressure on the vaginal wall. This term includes the possibility of a cystocoele, urethrocoele
- Posterior – weakening of the musculature and connective tissue or damage to the rectovaginal septum causes the rectum
to herniate into the vagina. This term includes the possibility of a rectocoele or enterocoele.
- Apical – the tissue supporting the uterus weakens and the uterus slips downward, placing pressure on the vagina;
usually associated with trauma in childbirth
- Vaginal vault prolapse – the roof of the vagina collapses, usually following hysterectomy (will also have an enterocoele
Any pelvic organ prolapse is then staged based on the maximum prolapse descent seen when the patient performs a Valsalva
manoeuvre. To clarify where the prolapse originates, a Sims speculum examination should be used. Referral to a Gynaecologist
or Urologist is likely to be necessary for further evaluation and treatment.
Managing urinary incontinence in females
Women with most types of incontinence are initially managed with pelvic floor muscle exercises and lifestyle modifications.
Pharmacological and surgical treatments then differ based on the type of incontinence.
General advice for all females with incontinence
The first step should be to recommend and offer support for weight loss for any patient with a BMI of ≥ 30 kg/m2, as
there is evidence of improved continence following weight loss.2
Other lifestyle advice focuses on reducing modifiable factors that may contribute to incontinence, such as:
Avoid excessive fluid intake and drinking late at night. N.B. Some patients may overcompensate or try to control incontinence
by reducing fluid intake below a normal level, which should be discouraged.
Reduce caffeine and alcohol intake – as both have a diuretic effect and may increase frequency
Avoid constipation by eating a varied diet and ensuring an adequate fibre intake (prescription of psyllium husk powder
may be useful) – constipation and faecal incontinence can exacerbate urinary incontinence.
Stop smoking (this may have the additional benefit of reducing coughing)
Increase physical activity, starting with very light exercise in individuals with stress incontinence – increased cardiovascular
fitness has been shown to reduce incontinence in some females8
Managing stress incontinence
As almost all stress incontinence in females is due to poor muscle tone in the pelvic floor muscles, exercises to strengthen
these muscles are an essential part of treatment.2 If this is ineffective or inappropriate, surgical options
may then be considered. Pharmacological treatments are not routinely used for stress incontinence.
Pelvic floor muscle exercises are first-line
Pelvic floor muscle exercises are an effective treatment for stress incontinence. Females undergoing these exercises
are more likely to report cure or improvement, better quality of life, fewer leakage episodes per day and have less urine
Referral to an appropriate practitioner (such as a Continence Adviser, Nurse Specialist in urogynaecology or Physiotherapist
specialising in women’s health) for an assessment of the appropriateness of a supervised programme of pelvic floor muscle
exercises is recommended. This programme should last for at least three months, be individualised and include instruction
on correct technique and a programme of at-home exercise.2
The patient may be given advice on how to start the exercises while they wait for their referral (see: “Pelvic
floor muscle exercises”).
After twelve weeks of exercises the patient’s pelvic floor muscle tone and the impact on incontinence should be reassessed.
Any patient who shows benefit should be encouraged to continue the exercises two to four times per week.2
A list of continence health professionals by region is available from the New
Zealand Continence Association:
Surgical and medical interventions
If the initial treatment with regular pelvic floor muscle exercises is unsuccessful, consider referral to an Urologist,
Urogynaecologist or Gynaecologist for urodynamic investigations and potential surgery.2
Surgical interventions for females with stress incontinence include:2
- Mid-urethral slings – a mesh tape is placed under the urethra through two to three small incisions in order to support
the urethra and “replace” the patient’s pelvic floor muscles. The tape increases sub-urethral support and
may help artificially recreate the pubo-urethral ligaments.
- Intramural urethral bulking agents – bulking materials are injected into the urethra and bladder neck, closing the
lumen of the urethra, to increase the tissue’s mass and increase outflow resistance. However, evidence about the effectiveness
and durability of this treatment is limited.16
All surgical and medical interventions are associated with some adverse effects, such as increased voiding frequency
and urgency incontinence.
Pharmacological treatment with duloxetine may be considered, although this medicine is not subsidised,
and is considered second-line to surgical treatment. Pharmacological treatment is only given to women who decline or are
not suitable for surgical treatment. Duloxetine can be effective in the short term, but there is no evidence of long-term
efficacy or safety data for use in women with incontinence, and the medicine is associated with a range of adverse effects.2,
Pelvic floor muscle exercises
Pelvic floor muscle exercises are used to strengthen the muscles under the uterus, bladder and bowel. They are used
in both males and females who have problems with urinary incontinence or bowel control, and following pregnancy and childbirth
in females. When performed correctly over several months, with good patient compliance, they can be effective in reducing
stress incontinence for most people with mild to moderate stress incontinence.7
Most pelvic floor muscle exercise interventions will be designed and initiated under the supervision of a Physiotherapist
or Continence Nurse.2 An individualised programme of exercises is usually developed for each patient.7 Where
referral is not possible or where the wait time for referral will be significant, an exercise regimen may be initiated
in primary care.
Pelvic floor muscle exercises can be described to the patient as tensing the muscles used to hold in urine. Advise
the patient that next time they are voiding to attempt to stop the flow in order to “visualise” the muscles that should
be tensed. Attempting to stop the flow of urine should only be used to assess whether the correct muscles are being contracted
and not as part of the exercise programme itself. Unless the technique is correctly demonstrated, some females may do
a Valsalva manoeuvre instead of contraction when they try to perform pelvic floor muscle exercises. If there is concern
that the patient is performing the technique incorrectly, muscle contraction can be assessed with a digital examination.
Strengthening exercises are performed by tensing, holding and then relaxing the muscles. The exercise programme should
comprise three sets of eight contractions, daily.2 Each contraction should be held for approximately ten
seconds. Between each contraction, the pelvic floor muscles are relaxed for several seconds. During contractions, it
is important to isolate the pelvic floor muscles. To do this, tell the patient to keep the gluteal and thigh muscles
relaxed during each contraction and to breath normally throughout the exercise.
Initially the patient may find it easiest to do the exercise while sitting or lying down, but once comfortable with
the exercise they can be done at any time, place or body position. In addition, advise the patient that it may be more
comfortable to empty their bladder prior to doing the exercise.
A Physiotherapist or Nurse may also suggest the use of biofeedback, electrical stimulation or vaginal cones as adjuncts
to exercise where appropriate, e.g. in females with an absent or very weak contraction, or to increase confidence that
the exercise is being done correctly.2
Commercially available products, such as Kegel balls and pelvic toners, are advertised as being effective for preventing
incontinence and strengthening the pelvic floor. It is difficult to quantify the efficacy of such products, and it is
advisable to discuss their use with a Physiotherapist first.
Managing urgency incontinence and overactive bladder
Urgency incontinence and overactive bladder can be initially managed with interventions for urgency and frequency, pelvic
floor muscle exercises and bladder training.
Pharmacological interventions can also be trialled, followed by surgical interventions where medicines are ineffective
or not tolerated.
Treat the cause and train the bladder
Urgency incontinence has a more varied underlying aetiology than stress incontinence, and in some females, incontinence
will be secondary to an infection or systemic condition. Treat or appropriately manage any underlying conditions that
may be contributing to incontinence, such as:2
- Lower urinary tract infection
- Sexually transmitted infection
- Neurological conditions, e.g. Parkinson’s disease and multiple sclerosis
- Systemic conditions, e.g. congestive heart failure and diabetes mellitus
- Functional and behavioural disorders, e.g. impaired mobility and excess alcohol use
- Adverse effects of medicines, e.g. diuretics
Following this, pelvic floor muscle exercises and bladder training are used to manage the symptoms of incontinence and
overactive bladder. Refer females with urgency incontinence or an overactive bladder to an appropriate specialist, e.g.
Continence Advisor, Nurse Specialist or Physiotherapist, for assessment and consideration of bladder training. The patient
should be asked to complete a bladder diary before starting bladder training. This is also useful in assessing response
Bladder training involves the patient becoming more aware of their voiding and incontinence patterns, and then learning
to control them.18 Scheduled times are set for voiding and then the times between voiding are gradually increased.
If urgency occurs, the patient may be encouraged to try to “hold-on” for a short time, e.g. ten minutes, before voiding.
Strategies to decrease urgency include: squeezing and holding the pelvic floor muscles or doing several squeezes quickly,
distraction, leaning forward slightly, keeping still, squeezing the fists tightly or pushing the ball of the foot hard
onto the floor.
Combined, these actions can reduce frequency and urgency.2 The effectiveness of bladder training varies
and there is currently insufficient evidence to assess the likelihood of cure or improvement with bladder training, however,
a Cochrane study concluded that it may be helpful and is a safe, low cost option.18, 19
If bladder training is ineffective or further control is needed, consider a trial of oxybutynin, an anticholinergic
medicine. Anticholinergic medicines are effective for treating urinary incontinence because they decrease muscular spasms
of the bladder, therefore suppressing urgency and overflow. Oxybutynin has been shown to reduce the symptoms of urgency
and increase bladder capacity.2 It is generally only appropriate for females with presumed detrusor overactivity
or overactive bladder with frequency, urgency and incontinence. It is used first-line in preference to newer anticholinergic
medicines due to a long history of use, a large evidence base for efficacy and lower cost.7 In addition, oxybutynin
must be trialled before other options to meet Special Authority criteria for subsidy for these medicines (see below).
The recommended starting dose of oxybutynin for incontinence is 5 mg, once daily, slowly titrated upward until effective,
generally 5 mg, three times daily. The maximum dose is 5 mg, four times daily.2, 10 In older patients the
initial dose should be 2.5 mg, twice daily, and only increased if necessary.10 Oxybutynin is available fully
subsidised as an oral tablet or liquid, and without subsidy as a twice-weekly transdermal patch. Oxybutynin is associated
with several adverse effects, most notably dry mouth, constipation and sedation, which often affects patient compliance
with treatment. Transdermal patches may have fewer adverse effects due to a slower release of oxybutynin. Oxybutynin is
contraindicated in people with bladder outflow obstruction, which can present in a similar way to urgency incontinence
in some people. Oxybutynin is also contraindicated in people with angle-closure glaucoma, toxic megacolon, ulcerative
colitis or gastrointestinal obstruction.10
Elderly patients are particularly susceptible to the effects of anticholinergics, and should have their current medicines
reviewed to avoid anticholinergic loading.2 Anticholinergic loading occurs in people taking multiple medicines
with anticholinergic effects; the combined effect of all anticholinergic medicines is additive and their adverse effects
become increasingly severe with greater load.
If oxybutynin is not tolerated or effective, consider other anticholinergic medicines,2 such as solifenacin
succinate, 5 mg, once daily, or tolterodine tartrate, 2 mg, twice daily.10 These medicines have a more favourable
adverse effect profile than oxybutynin because solifenacin and tolterodine are more selective for the bladder than oxybutynin.20 Both
solifenacin and tolterodine are subsidised subject to Special Authority criteria that require the patient to have first
trialled oxybutynin and found it to be intolerable or ineffective.10
Patients taking any anticholinergic medicine for incontinence should be reviewed after six weeks to assess the efficacy
of the medicine and the presence and severity of adverse effects.2
Other treatments can also be considered, such as intravaginal oestrogen.2 How oestrogen works to reduce
incontinence is not well understood. Oestrogen receptors have been identified in the tissues of the vagina, bladder, urethra
and muscles of the pelvic floor; the bladder in particular is strongly influenced by circulating oestrogen levels.21 It
is thought that intravaginal oestrogen administration may reverse or limit the long-term loss of muscle tone to the urethral,
pelvic and bladder muscle that occurs after menopause.21
The role of incontinence pads
Incontinence pads are used as an adjunct to temporarily manage symptoms in some people. Clinicians should ask older
female patients in particular about pad usage, as direct-to-consumer marketing and the easy availability of the products
has made their use common and it may deter patients from seeking appropriate treatment. People with well controlled incontinence
will usually not require incontinence pads. However, they can be recommended for the following reasons:2
- To manage urinary leakage while awaiting assessment and treatment
- To contain leakage while waiting for a treatment response
- For people with severe cognitive or mobility impairment the makes further assessment or treatment impossible
- For the long-term management of people who have trialled and not responded to all other treatment options
Whenever continence products are used, a variety of options should be discussed and trialled, with product choice based
on patient preference. A Cochrane review found that the design of the product affected its efficacy.23 Nappy-style
products (i.e. side opening) were found to be most effective for males and pull-ups (underwear-style products with a
smaller absorbency volume) or disposable pads were most effective and acceptable for females.23 Nocturnal
incontinence was best managed by nappy-style products for both males and females.23
Referral to a Continence Nurse specialist may be useful where continence pads need to be trialled. In addition, funding
for incontinence pads may be available from some district health boards (DHBs).
Surgical interventions for females with urgency incontinence and overactive bladder may be considered where more conservative
treatments have been ineffective. This includes botulinum toxin injected into the bladder, sacral nerve stimulation, augmentation
cystoplasty and, where all other treatments have been ineffective, urinary diversion.
Botulinum toxin, when injected into the bladder wall, can reduce the frequency and strength of muscle spasms. The injection,
given under anaesthesia, can be effective for nine months to one year. It appears to reduce bladder spasm and incontinence
in approximately 60% of patients.22 Botulinum toxin is associated with some adverse effects, the most significant
of which is temporary urinary retention.
Sacral nerve stimulation involves the implantation of a device that applies mild electrical stimulation to the sacral
reflex pathway of the bladder.2 Sacral nerve stimulation generally decreases urinary frequency and can reduce
the number of incontinent episodes.2
Augmentation cystoplasty is a surgical procedure that increases the capacity of the bladder and reduces overactivity.2 The
procedure involves grafting a section of tissue, usually from the small intestine or stomach, onto the top of the bladder.
It is a relatively uncommon procedure.
Urinary diversion surgery is a complex and invasive procedure that diverts urine away from the bladder, generally through
an ileal conduit (a passage made from a segment of the small intestine) into an external storage device (urostomy bag).
It is a “last resort” treatment and is generally reserved for people with continuous or complete incontinence, for whom
all other treatments have been trialled and been ineffective.
Urinary incontinence in males
The approach to investigation and treatment of urinary incontinence in males is similar to that for females.
Many males experience incontinence at some point in their lives. Incidence increases with age and with certain conditions,
particularly those involving the prostate. In males, incontinence is usually a subset of “lower urinary tract symptoms”
(LUTS), which includes post-void dribbling, obstruction and overflow, nocturia and urgency. The likelihood of a significant
underlying cause of incontinence is higher in males, and investigation of the cause is always necessary. Urinary incontinence
in males is usually related to either prostate abnormalities or a neurological condition. The most common cause of urinary
incontinence in males is benign prostatic hyperplasia, which causes incontinence, frequency and other LUTS due to the
enlarged prostate pushing against the bladder.1 Prostatectomy and radiation treatment of the prostate are
also significant contributors to male incontinence (84% of males who undergo radical prostatectomy will develop incontinence).25 Neurological
causes of incontinence include age-related changes that lead to bladder overactivity, diabetes and other systemic conditions
that reduce nerve function and neurological disorders such as stroke. More rarely, incontinence can be due to renal or
bladder conditions, such as malignancy or vesical calculi (bladder stones).26
The dominant types of incontinence in males are similar to those seen in females, i.e. stress, urgency and overflow
incontinence and bladder overactivity.
History and examination
Red flags for urinary incontinence in males should be assessed
and the patient referred if necessary (see: “Red flags for referral”).
As with females, the patient history should be used to assess the likelihood of an underlying cause,
the severity of the incontinence and the impact that the incontinence has on the daily life of the patient (see: “Patient
The history should also include questions on previous prostate conditions or surgery.7
Determining the type of incontinence present in males is similar to females and should be based on
when and why leakage occurs, e.g. if leakage occurs during exercise, stress incontinence is likely.
The general examination should focus on any non-genitourinary causes or conditions that may be contributing
to incontinence, e.g. obesity, stroke.
The external genitalia should be examined for signs of phimosis (the foreskin cannot be fully retracted
over the glans), balanitis (inflammation of the glans), hypospadias (a birth defect causing the urethral opening to be
abnormally placed on the ventral, or underside, of the penis), hernias, signs of infection or other abnormalities.26
A digital rectal examination is then recommended. Assess the size and consistency of the prostate and
examine for nodules, tenderness and any masses.26 The patient’s pelvic floor musculature should
also be assessed at this point, using the proxy measure of the patient’s anal tone. To do this, with the patient supine,
insert a finger one to two centimetres into the rectum (with the finger pad toward the coccyx) and assess the resting
tone of the sphincter before asking the patient to tense the muscles. This contraction should be held for five seconds.
Assess the relative strength and endurance of the muscle contraction. As for females, a grading scale may be used for
this, such as the Oxford grading scale.
Perform dipstick analysis of the urine in all males presenting with urinary incontinence to assess
the likelihood of a treatable underlying cause, e.g. infection.1, 26
Request serum creatinine, as renal dysfunction or abnormalities may be a contributing factor, if any
of the following are present:26
- Chronic urinary retention – this is suggested by overflow incontinence (e.g. bedwetting) or an enlarged bladder detected
on abdominal palpation or percussion
- Recurrent urinary tract infection
- History of urinary tract stones
The patient should be asked to complete a bladder diary.1 Further urodynamic testing such as flow testing
(uroflowmetry) may be requested in secondary care.
The management of urinary incontinence in males differs slightly from females as the likelihood of a significant underlying
pathology is relatively high, particularly if there is no history of prostatic surgery or irradiation.
Management is based on the primary type of incontinence.
Managing stress incontinence in males
When stress urinary incontinence is caused by prostatectomy, patients should be referred to a Continence
Nurse, Continence Physiotherapist or urology clinic for supervised pelvic floor muscle exercises.26 Pelvic
floor muscle exercises are very similar for both males and females. Exercises should be performed for at least three months
before considering more invasive treatment options.26
For further information see: “Pelvic floor exercises”.
When stress urinary incontinence is not caused by prostatectomy, the patient should be referred to
an Urologist for assessment to investigate the cause.26 This is due to the potential for a significant underlying
cause being present, such as prostate cancer or structural abnormalities.
Referral to an Urologist should still be considered in males with incontinence following prostatectomy, particularly
if behavioural treatments are ineffective. Surgical interventions are available for males with stress incontinence. These
are generally limited to male slings and artificial urinary sphincters.26 For males with mild to moderate
stress incontinence, male sling surgery has cure rates of 40 – 60%, with significant improvement in a further 10 – 40%.25 The
procedure is minimally invasive.25 The artificial urinary sphincter is also highly effective, with complete
continence achieved in 60 – 90% of males. However, this is a more invasive procedure and may be associated with greater
adverse effects, such as urethral atrophy and mechanical failure of the device.25
Managing urgency incontinence and overactive bladder in males
First exclude or manage all treatable causes of urgency incontinence, such as benign prostatic hyperplasia, neurological
conditions, current UTI or STI, vesical calculi or prostate or bladder cancer.26 This may involve multiple
consultations and temporary continence products can be offered while the cause of incontinence is being investigated (see:
Benign prostatic hyperplasia can be treated with alpha-blockers such as doxazosin or terazosin. Finasteride (Special
Authority) may also be considered if alpha-blockers are not tolerated. N.B. Alpha blockers can potentially contribute
to stress incontinence.
Where a preventable underlying cause is not identified, referral to a Physiotherapist or Nurse Specialist in incontinence
for bladder training is recommended.26 Bladder training is similar for both males and females.
If symptoms persist despite bladder training, or where bladder training is not possible, consider a trial of oxybutynin.
If pharmacological treatment is ineffective, referral to an Urologist is recommended.26
Surgical and medical options for the treatment of urgency incontinence in males include botulinum injections into the
bladder wall, sacral nerve stimulation and augmentation cystoplasty.26
The New Zealand Continence Association (NZCA) has further information and resources for practitioners including templates
of bladder diaries and examples on pelvic floor muscle exercise programmes. See: