People with COPD are generally underweight, have reduced muscle mass and are often malnourished, leading to other health problems. Opportunities for dietary intervention should be explored, aiming at early detection and early treatment of involuntary weight loss.
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Key Reviewer: Dr Lisa Houghton, Lecturer: Department of Human Nutrition, University of Otago
- Weight loss is common in people with COPD and nutritional management plays an important role.
- Weight loss is related to decreased exercise capacity, health status and increased morbidity.
- Opportunities for dietary and nutritional interventions in COPD management should be explored, aiming at early
detection and early treatment of involuntary weight loss.
Weight loss is common in people with COPD
In people with chronic obstructive pulmonary disease (COPD), energy requirements have been reported to be 15�20% above
normal needs due to the increased energy required for breathing. People with COPD are generally underweight and have reduced
muscle mass.1 One UK based study showed that 23% of subjects with COPD were classified as malnourished. The
malnourished subjects had lower lung function measurements, suffered more dietary problems and had lower nutritional intake
compared with the adequately nourished subjects.2
Careful balancing of caloric intake is required. One study showed that a total caloric intake in excess of 50% above
need was associated with poorer outcomes, while caloric intake of 30% above need was beneficial.3
Referral to a dietitian is recommended to establish an appropriate diet for a person with COPD who is malnourished.
Eating small, frequent meals may help to reduce dyspnoea
As COPD progresses, many people find that breathing becomes more difficult if they eat a heavy meal, so in this situation,
eating frequent, small and nutritious (high energy, high protein) meals is best (see �High
energy, high protein food ideas�). If people with COPD are not managing to keep their weight above a desired level
they may require dietary assistance.4
Evidence for nutritional support is limited
Evidence supporting the use of nutritional supplements for people with COPD is limited. A 2005 Cochrane systematic review
found no evidence that nutritional supplementation makes a significant difference to weight gain or health outcomes in
people with COPD.5
Despite this lack of evidence, the UK National Institute for Clinical Excellence guidelines for the management of COPD
in adults, suggest that nutritional supplements may be considered for people with a BMI less than 20 kg/m2 and these patients
should also be encouraged to exercise regularly to build muscle mass.6
The American Thoracic Society also recommends considering nutritional supplementation for people with COPD who have
involuntary weight loss of more than 10% in the last six months or more than 5% in the past month.7
Nutritional management of patients with severe COPD is challenging and interventions should be extended to the early
detection and further prevention of weight loss before patients become malnourished.
A late manifestation of COPD is hypercapnia. It is caused by a reduction in ventilatory drive and is a feature of severe
In theory, under ideal conditions, dietary fat utilisation produces less CO2 per O2 molecule consumed
than carbohydrate. However, most studies indicate that consuming excess calories is a more important contributor to increased
CO2 production than the fat composition of the food.3
Higher fat supplements have been found to delay gastric emptying. This may be important in determining patient tolerance
of these formulas as a delay in gastric emptying can lead to extended periods of abdominal distention.
Pulmocare is a high fat, low carbohydrate formula designed to minimise CO2 retention in chronic or acute
respiratory insufficiency. Pulmocare is the only COPD specific product available in New Zealand.
Subsidy for Pulmocare (which contains 1.5kcal/mL in 237mL cans) is available from a relevant specialist for patients
who have COPD and have hypercapnia and need the supplement as part of, or as a complete, diet.
GPs role in the nutritional care of people with COPD
Encourage patients with COPD to make and maintain dietary changes such as eating a high energy, high protein diet
or eating small, frequent meals, to minimise involuntary weight loss and nutritional depletion.
Advise people with COPD who become breathless when eating to eat frequent small meals.
Consider oral nutritional supplements for patients with a low BMI, significant involuntary weight loss or those who
develop hypercapnia. For more information on oral supplements see “Which oral nutritional
supplement for malnutrition should be used?”.
- Hugli O, Schutz Y, Fitting JW. The daily energy expenditure in stable chronic obstructive pulmonary disease. Am J
Respir Crit Care Med 1996; 153:294�300.
- Cochrane W, Afolabi O. Investigation into the nutritional status, dietary intake and smoking habits of patients with
chronic obstructive pulmonary disease. J Hum Nutr Diet. 2004 Feb;17(1):3-11.
- Mallampalli A. Nutritional Management of the Patient With Chronic Obstructive Pulmonary Disease. Nutr Clin Prac 2004;19(6):550-6.
- Thoracic Society of Australia and New Zealand and Australian Lung Foundation. The COPDX plan: Australian and New
Zealand guidelines for the management if chronic obstructive pulmonary. April 2006. Available from:
- Ferreira IM, Brooks D, Lacasse Y, Goldstein RS, White J. Nutritional supplementation for stable chronic obstructive
pulmonary disease. Cochrane Database Syst Rev 2005; 1.
- National Institute for Clinical Excellence (NICE). Management of chronic obstructive pulmonary disease in adults
in primary and secondary care. February 2004
. Available from: http://www.nice.org.uk/ (Accessed July 2008).
- American Thoracic Society/European Respiratory Society Statement on Pulmonary Rehabilitation. Am J Respir Crit Care
Med 2006; 173: 1390�1413.